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Pancreas Cancer

Pancreas Cancer Surgeon in Nashik, MaharashtraPancreas Cancer Surgeon in Nashik, Maharashtra

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Pancreas Cancer

Pancreas Cancer

What is Pancreas Cancer ?

Pancreatic cancer originates when abnormal cells in the pancreas begin to grow uncontrollably, forming a malignant tumor. The pancreas, a vital organ located behind the stomach, plays a crucial role in digestion and blood sugar regulation.

Types of Pancreatic Cancer

Pancreatic cancer is primarily categorized into:

  • Exocrine Tumors: The most prevalent form, with pancreatic ductal adenocarcinoma being the most common subtype.
  • Endocrine Tumors: Also known as pancreatic neuroendocrine tumors (NETs) or islet cell tumors, these are less common and originate from hormone-producing cells.
Symptoms

In its early stages, pancreatic cancer often remains asymptomatic. As the disease progresses, individuals may experience:

  • Jaundice: Yellowing of the skin and eyes due to elevated bilirubin levels.
  • Abdominal or Back Pain: Discomfort in the upper abdomen or back regions.
  • Unintended Weight Loss: Significant weight reduction without changes in diet or exercise.
  • Loss of Appetite: Decreased desire to eat.
  • Nausea and Vomiting: Feeling sick and vomiting.
  • New-Onset Diabetes: Development of diabetes not associated with weight gain.
Risk Factors

Several factors may elevate the risk of developing pancreatic cancer:

  • Smoking: Tobacco use significantly increases risk.
  • Chronic Pancreatitis: Long-term inflammation of the pancreas.
  • Diabetes: Particularly type 2 diabetes.
  • Family History: A history of pancreatic cancer in close relatives.
  • Obesity: Excess body weight.
  • Age: Individuals over 65 are at higher risk.
Diagnostic Tests

To diagnose pancreatic cancer, healthcare providers may employ:

  • Imaging Tests: CT scans, MRI, and PET scans to visualize the pancreas.
  • Endoscopic Ultrasound (EUS): A procedure using an endoscope with an ultrasound device to obtain images and tissue samples.
  • Biopsy: Removal of a small tissue sample for laboratory analysis.
  • Blood Tests: Assessing for tumor markers like CA 19-9, though not definitive for diagnosis.
Stages of Pancreatic Cancer

Staging determines the extent of cancer spread:

  • Stage 0: Abnormal cells present but not yet cancerous.
  • Stage I: Cancer confined to the pancreas.
  • Stage II: Cancer has spread to nearby tissues and possibly lymph nodes.
  • Stage III: Cancer has spread to major blood vessels and lymph nodes.
  • Stage IV: Cancer has metastasized to distant organs.
Treatment Options

Treatment depends on the cancer’s stage and the patient’s overall health:

  • Surgery: Procedures like the Whipple operation (pancreaticoduodenectomy) to remove the tumor.
  • Radiation Therapy: Using high-energy beams to target and kill cancer cells.
  • Chemotherapy: Drugs administered to destroy cancer cells, often combined with other treatments.
  • Targeted Therapy: Medications designed to attack specific cancer cell abnormalities.
  • Immunotherapy: Treatments that enhance the body’s immune response against cancer cells.
Surgical Techniques

The choice of surgical procedure depends on the tumor’s location and stage:

  • Whipple Procedure: Removal of the pancreas head, duodenum, gallbladder, and bile duct.
  • Distal Pancreatectomy: Removal of the pancreas body and tail, often with the spleen.
  • Total Pancreatectomy: Complete removal of the pancreas, necessitating lifelong enzyme and insulin replacement.

Early detection and a comprehensive treatment plan are crucial for improving outcomes in pancreatic cancer patients.

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